... cell lines. Inhibition of miR-224-5p expression by microRNA inhibitors could inhibit the proliferation, migration, and invasion of ccRCC cells. Besides, it was validated by dual-luciferase assay in which miR-224-5p directly targeted OCLN gene. The expression of OCLN was downregulated in ccRCC cells...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. miR-182 Acute kidney injury Ischemia reperfusion injury FoxO3 Apoptosis Proliferation Acute kidney injury (AKI) is a major clinical event, and there is currently...

...Yangle Li; Xiaokun Zhao; Huiting Tang; Zhaohui Zhong; Lei Zhang; Ran Xu; Songchao Li; Yi Wang Objectives: It was the aim of this study to explore the effects of 3-(5′-hydroxymethyl-2′-furyl)-l-benzyl indazole (YC-1) on transcription activity, cell proliferation and apoptosis of hypoxic human...

... cancers is unclear. Here, we investigated the role of protein kinase C (PKC) in ATO-induced apoptosis and inhibition of proliferation in bladder cancer cells. Methods: T24 human bladder carcinoma cells were incubated with different concentrations of ATO in the presence or absence of PMA (PKC activator...