Fig. 1.
This figure shows temporal trends in type 2 diabetes mellitus (T2DM) among patients undergoing nephroureterectomy for upper tract urothelial cancer in the National Inpatient Sample between 2004 and 2019. Two groups are displayed: non-insulin-dependent T2DM (orange) and insulin-dependent T2DM (red). Non-insulin-dependent T2DM was consistently more common, increasing modestly from 13.6% in 2004 to 18.0% in 2019. Insulin-dependent T2DM remained much less frequent but increased steadily from 0.1% in 2004 to 4.2% in 2019. Trend analyses demonstrated a small annual increase for non-insulin-dependent T2DM (+1.1% per year; 95% CI: 0.1%–2.1%; p = 0.045) and a substantially larger annual increase for insulin-dependent T2DM (+11.8% per year; 95% CI: 8.6%–15.6%; p <0.001).

Estimated annual percentage change of type 2 diabetes mellitus (T2DM) stratified according to insulin dependence in upper tract urothelial cancer patients undergoing nephroureterectomy within the National Inpatient Sample (NIS) from 2004 to 2019.

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