miR-205 and VEGFA expression in RCC. a miR-205 is significantly downregulated in malignant tissue of an in-house RCC cohort. bVEGFA is significantly upregulated in cancerous lesions. c Data from the TCGA ccRCC cohort: VEGFA is significantly overexpressed in malignant tissue (n = 523) compared to benign tissue (n = 100). Apart from VEGFA upregulation, miR-205 is significantly downregulated in ccRCC specimens – resulting in a significant negative correlation of VEGFA and miR-205 expression. FPKM, fragments per kilobase per million mapped reads; RPM, reads per million mapped reads.