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Keywords: parC gene
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Journal Articles

Genotypic Evolution in a Quinolone-Resistant Neisseria gonorrhoeae Isolate from a Patient with Clinical Failure of Levofloxacin Treatment

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Masatoshi Tanaka, Kazuyuki Sagiyama, Masashi Haraoka, Takeshi Saika, Intetsu Kobayashi, Seiji Naito
Journal: Urologia Internationalis
Urol Int (1999) 62 (1): 64–68.
https://doi.org/10.1159/000030344
Published Online: 28 July 1999
... the gyrA and parC genes. Moreover, we assayed the intracellular levofloxacin and norfloxacin accumulation level in these isolates. The pretreatment isolate contained three substitutions compared to susceptible wild-type isolate, including serine to phenylalanine at position 91 and aspartic acid...
View article titled, Genotypic Evolution in a Quinolone-Resistant Neisseria gonorrhoeae Isolate from a Patient with Clinical Failure of Levofloxacin Treatment
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