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Keywords: miR-21
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Journal Articles
Metformin-Derived Growth Inhibition in Renal Cell Carcinoma Depends on miR-21-Mediated PTEN Expression
Available to PurchaseSubject Area:
Further Areas
Charis Kalogirou, Daniel Schäfer, Markus Krebs, Florian Kurz, Andreas Schneider, Hubertus Riedmiller, Burkhard Kneitz, Daniel Vergho
Journal:
Urologia Internationalis
Urol Int (2016) 96 (1): 106–115.
Published Online: 24 October 2015
... the influence of miR-21 and its target gene PTEN on MF effects in CAKI-1 and CAKI-2 cells. Methods: Proliferation assays (MTS) and qRT-PCR after transient transfection with pre- and anti-miR-21 and MF treatment were conducted. AMPK -dependency was assessed via transfection of siAMPK. The expression of PTEN...
