..., Kumamoto University Medical School, Kumamoto, Japan Key Words. Urinary prostaglandin E Furosemide Vasopressin Dehydration Indomethacin Abstract. The role of the renal prostaglandin (PG) system in the renal effects of furosemide was assessed by using indomethacin, an inhibitor of PG synthetase...

... exchange caused by furosemide in the distal nephron might stimulate the renal K-K system to result in increasing synthesis of PGE, which would, at least in part, participate in the diuretic and natriuretic effects of furosemide. Urinary kallikrein Urinary prostaglandin E Furosemide Potassium-sodium...