.... The ultrastructural alterations aggravated along the course of ureteric obstruction. Intriguingly, the ultrastructural changes were significantly milder in the treated rats. We conclude that the administration of furosemide might increase the severity of hydroureter, but it does not accelerate the ureteric damage...

... Endothelin in Long-Term Complete Ureteric Obstruction in the Young Rat Key Words Ureteric obstruction Renal endothelin Weanling rats Abstract Complete obstruction of one ureter was created in 3-week-old weanling rats. The endothelin concentration in the renal tissue was measured by radioimmu­ noassay...