...Jianping Liu; Weijian Zhou; Peng Zhang; Wei Zhang; Congwang Chang; Guanghua Fu Background: There is limited research into the efficacy and safety of tadalafil combined with tamsulosin for the treatment of lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH...

...Takahira Kuno; Kenji Tamura; Hideo Fukuhara; Satoshi Fukata; Shingo Ashida; Takashi Karashima; Kohji Sawada; Masaharu Yasuda; Hironobu Watanabe; Fumito Komatsu; Hajime Kuroiwa; Motoaki Saito; Keiji Inoue Objective: No reports have evaluated the treatment effects of tadalafil by age group...

... replacement on ED patients with VDD is uncertain. As far as we know, there is no study yet in the literature regarding the addition of vitamin D to phosphodiesterase type 5 inhibitors in the treatment of ED patients with VDD. In this study, we investigated whether adding vitamin D to daily tadalafil treatment...

...Naoki Wada; Daiki Kikuchi; Jo Tateoka; Noriyuki Abe; Masaki Watanabe; Gaku Tamaki; Masafumi Kita; Hidehiro Kakizaki Objectives: We examined the persistence rate with tadalafil for treatment of male lower urinary tract symptoms (LUTS) and explored the factors relevant to withdrawal. Patients...

...Zhufeng Peng; Lu Yang; Qiang Dong; Qiang Wei; Liangren Liu; Bo Yang Introduction: To compare the efficacy and safety between tadalafil once-a-day and tadalafil on-demand dosing regimen in patients with ED. Materials and Methods: A systematic search of Medline, Embase, and Cochrane Library...

...Levent Ozcan; Emre Can Polat; Efe Onen; Ramazan Kocaaslan; Alper Otunctemur; Mustafa Cekmen; Ceyla Eraldemir; Emin Ozbek Purpose: In this study, we evaluated the effect of 5 mg tadalafil once daily in men with premature ejaculation (PE). Methods: Thirty married men with lifelong PE and 30 healthy...

...Guangyu Li; Haiyan Lan; Jihong Liang; Chengmei Zhang; Cunchao Huang Objectives: To assess the efficacy of tadalafil de-escalation in the therapeutic effects of psychogenic erectile dysfunction (ED) during the 3 months extension phase. Methods: A total of 90 men with mild to severe psychogenic ED...

...Semra Yigitaslan; Orhan Ozatik; Fikriye Yasemin Ozatik; Kevser Erol; Basar Sirmagul; Ali Barbaros Baseskioglu Introduction: The protective and/or therapeutic potential of tadalafil (TDL) on cyclophosphamide (CP)-induced hemorrhagic cystitis (HC) and testicular dysfunction in rats was evaluated...

...Yang Dong; Lin Hao; Zhenduo Shi; Gang Wang; Zhiguo Zhang; Conghui Han Objective: To evaluate the efficacy and safety of tadalafil monotherapy for lower urinary tract symptoms secondary to benign prostatic hyperplasia (LUTS/BPH). Methods: A comprehensive search was done to identify randomized...

...Mehmet Guzeloglu; Fatih Yalcinkaya; Soner Atmaca; Alper Bagriyanik; Suleyman Oktar; Oguz Yuksel; Iyad Fansa; Eyup Hazan Acute renal failure due to ischemia-reperfusion (I/R) injury is a common complication in cardiovascular surgery. We determined the influence of tadalafil on renal injury...

...Ali Ayyıldız; Mahir Kaya; Ersagun Karagüzel; Ali Bumin; Turgay Akgül; Zeki Aklan; Cankon Germiyanoğlu Introduction: To investigate the effect of tadalafil on Resistivity Index (RI) and Pulsatility Index (PI) in partial unilateral ureteral obstruction (PUUO). Methods: Twelve New Zealand rabbits were...