.... The immunohistochemistry positive test to vimentin, cytokeratins AE1 and AE3 confirms the diagnosis of bladder leiomyosarcoma. Cyclophosphamide is an oxaphorine chemotherapy agent used in leukemia, lymphoma, retinoblastoma, and autoimmune diseases like systemic lupus erythematosus, Wegener's granulomatosis...

... following enzymatic dissocation, characterised by immunohistochemistry and electron microscopy, and further studied for abnormal p53 or retinoblastoma genes. Cells in culture were shown to maintain the morphological attributes of the primary lesion, including the overproduction of mitochondria. Despite...

...Stacey L. Bléoo; Roseline Godbout; David Rayner; Yahya Tamimi; Ronald B. Moore We report a rare case of leiomyosarcoma in the bladder which occurred in an 18-year-old female with a prior history of retinoblastoma (RB). Molecular characterization of this tumor displayed a homozygous RB deletion...