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Keywords: Promoter region
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Journal Articles
Lack of Evidence for the Association of E-Cadherin Gene Polymorphism with Increased Risk or Progression of Prostate Cancer
Available to PurchaseSubject Area:
Further Areas
Hiromasa Tsukino, Yoshiki Kuroda, Hirohisa Imai, Hiroyuki Nakao, Delai Qiu, Yasuhiro Komiya, Hisato Inatomi, Takashi Hamasaki, Kiyotaka Kohshi, Yukio Osada, Takahiko Katoh
Journal:
Urologia Internationalis
Urol Int (2004) 72 (3): 203–207.
Published Online: 15 April 2004
... is associated with tumor grade and advanced clinical stage. A –160 C→A polymorphism in the promoter region of E-cadherin has been shown to decrease gene transcription. This allelic variation may be a potential genetic marker that can help identify those individuals at higher risk for invasive/metastatic disease...
