... in the understanding of IC/BPS is urgent.” This review analyses such a paradigm shift. Summary: The paradigm shift began with the serendipitous cure of Hunner’s lesion in a woman with a diagnosis of posterior fornix syndrome (PFS) and uterine prolapse. Retrospective analysis of surgical data from eight PFS studies...

... the cure of IC/BPS. Scheffler et al. applied the diagnostic and surgical criteria of the posterior fornix syndrome (PFS) [ 5 ], a component of the integral theory of female urinary incontinence. During preoperative assessment, Scheffler utilized the speculum test to mechanically support the uterosacral...

...Klaus Goeschen; Darren M. Gold; Bernhard Liedl; Alexander Yassouridis; Peter Petros Background: The posterior fornix syndrome (PFS) was first described in 1993 as a predictably occurring group of symptoms: chronic pelvic pain (CPP), urge, frequency, nocturia, emptying difficulties/urinary retention...

... between Hunner’s ulcer and known pain conditions associated with USL laxity. The original intention was to cure the “posterior fornix syndrome” (PFS), uterine prolapse, and associated pain and bladder symptoms by USL repair. A speculum inserted preoperatively into the posterior fornix alleviated pain...

... may be consistent with symptoms of the posterior fornix syndrome, which comprises 4 main symptoms: micturition difficulties, urge/frequency, nocturia, chronic pelvic pain, all consequent on USL laxity. Surgical cure of OAB and UAB is inconsistent with existing definitions, which imply pathogenesis...