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Keywords: P-170 glycoprotein
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Journal Articles

Circumvention of Multidrug Resistance Mediated by P-170 Glycoprotein Using Calcium Antagonists in Primary Human Renal Cell Carcinoma

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Gerald H. Mickisch, Jutta Kössig, Reinhold K. Tschada, Gerhard Keilhauer, Erich Schlick, Peter M. Alken
Journal: Urologia Internationalis
Urol Int (1991) 47 (3): 118–125.
https://doi.org/10.1159/000282204
Published Online: 03 February 2010
...Gerald H. Mickisch; Jutta Kössig; Reinhold K. Tschada; Gerhard Keilhauer; Erich Schlick; Peter M. Alken In experimental cell lines and in some human tumors, calcium antagonists reversed multidrug resistance mediated by P-170 glycoprotein in vitro. So far, clinical trials have not been very...
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Journal Articles

P-170 Glycoprotein, Glutathione and Associated Enzymes in Relation to Chemoresistance of Primary Human Renal Cell Carcinomas

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G. Mickisch, H. Bier, W. Bergler, M. Bak, R. Tschada, P. Alken
Journal: Urologia Internationalis
Urol Int (1990) 45 (3): 170–176.
https://doi.org/10.1159/000281701
Published Online: 02 February 2010
...G. Mickisch; H. Bier; W. Bergler; M. Bak; R. Tschada; P. Alken High intrinsic chemoresistance contributes to the dismal outcome of patients with disseminated renal cell carcinoma (RCC). In experimental cell lines, two defined defence mechanisms, P-170 glycoprotein and glutathione metabolism, have...
View article titled, P-170 Glycoprotein, Glutathione and Associated Enzymes in Relation to Chemoresistance of Primary Human Renal Cell Carcinomas
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