... expression in cultured renal tubular epithelial cells exposed to oxalate and calcium oxalate monohydrate (COM) crystals. Methods: NRK-52E cells were cultured and exposed to medium containing oxalate or COM for 1, 3, 6, 12 and 24 h. The levels of MGP mRNA expression were quantified using real-time PCR (RT-PCR...

...Robert G. Hahn; Martina Sikk One metabolic pathway for glycine leads to glyoxylate which is the precursor of oxalate. To investigate whether absorption of glycine solution in transurethral operations may promote precipitation of calcium oxalate stones, we collected urine for 24 h before and after...

...O. Schmucki; R. Asper The bases of a real metaphylaxis in the renal stone diseases are the analysis of stones and the research of metabolism in blood plasma and urine. The greatest part of the stones analyzed may be classified in four groups: oxalate, phosphate, uric acid and cystine...

...William G. Robertson Urinary stone disease is a multifactorial disorder arising essentially from an abnormal combination of a number of urinary risk factors. In the case of calcium urolithiasis the main risk factors are a low urine volume, a high urinary pH, increased excretions of calcium, oxalate...

...H.H. Knispel; R. Fitzner; M. Kaiser; M. Butz An acute acid load was used to evaluate potential chemical differences of urinary composition in recurrent oxalate stone formers and healthy controls. After intake of ammonium chloride, total calcium, ionized calcium and magnesium increased and citrate...

...H. Osswald; R. Hautmann The renal handling of oxalate was studied by the injection of 14 C-oxalate together with inulin as a glomerular marker into the renal artery in 6 patients. From the recovered amounts of the injected substances in the urine, time-concentration curves were constructed. Oxalate...

...A. Hodgkinson The compostion of 142 calculi from Sudan, Thailand, Indonesia and Saudi Arabia has been determined by qualitative and quantitative chemical analysis. Calcium oxalate was the commonest constituent of both kidney and bladder stones, followed by magnesium ammonium phosphate, ammonium...

...-fat diet. The treatment reduced urinary oxalate excretion to the normal range. Subsequently, 2 patients reduced the dose of calcium supplementation at their own discretion and consequently developed renal stones again together with hyperoxaluria. Based on these observations, we believe...