...Tohru Umekawa; Takanori Yamate; Naoya Amasaki; Kenjiro Kohri; Takashi Kurita We had sequenced a cDNA of calcium oxalate urinary stone protein extracted with 0.1 M EDTA. cDNA sequences showed complete homology between urinary stone protein and human osteopontin (OPN, bone sialoprotein I...

...E. Konya; N. Amasaki; T. Umekawa; M. Iguchi; T. Kurita Using seed crystal method, whole-urine method, and scanning electron microscopy, the inhibitory effects of sialic acid and osteopontin (OPN) on aggregation/growth of CaOx crystals were investigated. Using the seed crystal method, sialic acid...

..., instructions or products referred to in the content or advertisements. Rat kidney cell NRK-52E Calcium oxalate Osteopontin Original Paper Urol Int 2001;67:73 76 Received: August 30, 2000 Accepted: January 19, 2001 Calcium Oxalate Crystal Attachment to Cultured Rat Kidney Epithelial Cell, NRK-52E...

...Keiichi Tozawa; Yasuyuki Yamada; Noriyasu Kawai; Takehiko Okamura; Kosuke Ueda; Kenjiro Kohri Objectives: Osteopontin (OPN), a secreted adhesive glycoprotein, has been shown to be produced in excessive amounts in a variety of experimental models of malignancy. Increased levels of OPN exist in blood...

...T. Yamate; K. Kohri; T. Umekawa; E. Konya; Y. Ishikawa; M. Iguchi; T. Kurita We recently reported that the addition of the protein osteopontin (OPN) resulted in an increase in the deposition of calcium oxalate (CaOx) crystals on the surface of Madin Darby canine kidney (MDCK) cells. To determine...