..., histologically no differences were visible between groups II and III. Our experiment shows a significant growth-inhibiting effect of the plant extract for human BPH tissue in our model (p < 0.05). We conclude that the nude mouse model can be useful for the evaluation of systemic therapy modalities of human...

...) and with the development of nude mouse model for studying HRCC metastasis. The SN12C HRCC line contained heterogeneous subpopulations of cells with different metastatic potential and cells derived from spontaneous lung metastases were in general more metastatic than cells of the SN12C parental line. Nude mice were useful...

..., Institute of Clinical Medicine and bSchool of Medicine, University ofTsukuba; Department of Surgery, Tsukuba Municipal Hospital, Ibaraki. Japan Key Words. Bone resorption Renal cell carcinoma Nude mouse Abstract. The high incidence of metastatic bone disease in urological cancer makes it necessary...