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Keywords: Mutations
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Journal Articles

Sensitivity and Specificity of P53 Protein Detection by Immunohistochemistry in Patients with Urothelial Bladder Carcinoma

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Antonio S. Salinas-Sánchez, Manuel Atienzar-Tobarra, Juan G. Lorenzo-Romero, Francisco Sánchez-Sánchez, José M. Giménez-Bachs, María J. Donate-Moreno, Héctor Pastor-Navarro, Ibrahim Hernández-Millán, Miguel Segura-Martín, Julio Escribano-Martínez
Journal: Urologia Internationalis
Urol Int (2007) 79 (4): 321–327.
https://doi.org/10.1159/000109717
Published Online: 22 November 2007
... polymorphism (PCR-SSCP) of exons 5–9 of the p53 gene, with automatic sequencing done on any mutated samples. Immunohistochemistry (IHC) was also performed using anti-human P53 monoclonal antibody, and the diagnostic performance of this test was analyzed by a ROC curve, using the presence of p53 mutations found...
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