...Chunru Xu; Zhenpeng Zhu; Lanruo Lin; Tongde Lv; Tianyu Cai; Jian Lin Background: The high recurrence of a urethral stricture after direct vision internal urethrotomy (DVIU) has been a problem for years. Mitomycin C (MMC) is an excellent antifibrosis antigen that has been used in many fields...

.... Methods: When a small (≤1 cm) papillary recurrence of a NMIBC was diagnosed, the patient could choose between immediate transurethral resection of the bladder (TURB) or four weekly intravesical instillations with mitomycin C (MMC) or epirubicin (ERC). Control cystoscopy was scheduled 2-3 weeks after...

...-refractory neoplasms, cystectomy is the gold standard. In this study the effects of thermochemotherapy with mitomycin C were evaluated in high-risk bladder cancer nonresponders to previous therapy. Patients and Methods: Between January 2006 and December 2009, 30 patients were enrolled with recurrent stage...

...Marco Racioppi; Andrea Volpe; Emanuele Cappa; Daniele D’Agostino; Francesco Pinto; Alessandro D’Addessi; Emilio Sacco; PierFrancesco Bassi Objective: The aim of this work was to verify the tolerability and the preliminary clinical results of intensive intravesical instillations of a mitomycin C...

...R. Minervini; R. Felipetto; L. Viganò; S. Pampaloni; L. Fiorentini A total of 208 patients with superficial transitional-cell carcinoma of the bladder (STCC) after transurethral resection were treated with 30 mg intravesical instillations of mitomycin C (MMC) weekly for 8 weeks, followed by monthly...

...Toshiyasu Amano; Katsusuke Naito; Kiyoshi Koshida; Kazuto Kunimi; Hiroshi Morishita; Haruo Hisazumi We treated a 61-year-old patient with a diagnosis of bilateral ureteral carcinoma in situ with percutaneous perfusions of mitomycin C. After 16 sessions of mitomycin C therapy instilled through...

... mitomycin C (MMC). The instillation time was 0.5 and 1.0 h. The resorption of MMC by the bladder wall was not influenced by the instillation time. There was no cumulative effect on MMC resorption observed in consecutive instillations. Less than 1 % of the instilled dose of MMC was resorbed. The maximum...

.... Mitomycin C (MMC) is a widely used agent for the adjuvant treatment of bladder tumors. A patient who developed MMC-induced bladder perforation and perivesical necrosis after an uneventful endoscopic tumor is presented. We suggest that the possible reason for such a complication could be deep resection...

...P. Oliveira; C. Palmeira; A. Colaço; L.F. De la Cruz P; C. Lopes Aim: To study cell proliferation and DNA content in urothelial lesions identified after repeated intravesical instillations of mitomycin C (MMC) and bacillus Calmette-Guérin (BCG) in normal rat urothelium. Material and Methods...

...Sven Oehlschläger; A. Loessnitzer; Michael Froehner; Oliver W. Hakenberg; Andreas Manseck; Manfred P. Wirth We report a case of distal ureteral stenosis after transurethral resection of a small bladder tumor near the left ureteral orifice and early postoperative mitomycin C instillation...

...R. Hurle; A. Manzetti; A. Losa; E. Micheli; A. Ranieri; D. Chinaglia; A. Lembo Objective: The present study evaluated the long-term results of intravesical mitomycin C (MMC) instillation after transurethral resection (TUR) in 242 consecutive patients with superficial bladder cancer at high risk...