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Keywords: High frequency of microsatellite instability
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Journal Articles
The First Case of Lynch Syndrome-Associated Penile Cancer Harboring a Heterozygous PMS2 Frameshift Variant
Available to Purchase
Journal:
Urologia Internationalis
Urol Int (2025) 109 (1): 97–101.
Published Online: 02 September 2024
... to metastatic disease. He has a family history of colon cancer and brain cancer. Comprehensive genomic sequencing of his tumor specimen identified 19 somatic mutations with a high tumor mutation burden (14.03 mutations per Mb) and a high frequency of microsatellite instability. Additionally, a germline PMS2...
