... heterogeneity of the carbohydrate moiety. However, the glycosylation patterns were found to be essentially similar between seminoma and normal testis. On isoelectric focusing, differences in migration patterns were revealed between seminoma-derived and normal testis-derived PLAP-like enzyme as well as between...

...S. Naito; J. Kumazawa; A.C. von Eschenbach; I.J. Fidler The demonstration that cancers are biologically heterogeneous has a far-reaching implication for therapy. We reviewed recent data from our laboratories that deal with metastatic heterogeneity of human renal cell carcinoma (HRCC...