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Keywords: GSTM1
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Journal Articles
A Germline Homozygote Deletion of the Glutathione-S-Transferase Mu1 Gene Predisposes to Bladder Cancer
Available to PurchaseSubject Area:
Further Areas
N. Aydin Mungan, Katja K.H. Aben, Esther Beeks, Ellen Kampman, Annelies Bunschoten, Marion Bussemakers, J. Alfred Witjes, Lambertus A.L.M. Kiemeney
Journal:
Urologia Internationalis
Urol Int (2000) 64 (3): 134–138.
Published Online: 02 June 2000
... of bladder cancer may be modified by the activity of carcinogen metabolizing enzymes. The glutathione-S-transferase Mu1 enzyme (GSTM1) detoxifies arylepoxides which are formed after exposure to certain polycyclic aromatic hydrocarbons and possibly aromatic amines. Approximately 40% of Caucasians lack GSTM1...
