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Keywords: DNA methyltransferase inhibitor
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Journal Articles
An Epigenetic Screen Unmasks Metallothioneins as Putative Contributors to Renal Cell Carcinogenesis
Available to PurchaseSubject Area:
Further Areas
Imad Alkamal, Odiljon Ikromov, Angelika Tölle, Tom Florian Fuller, Ahmed Magheli, Kurt Miller, Hans Krause, Carsten Kempkensteffen
Journal:
Urologia Internationalis
Urol Int (2015) 94 (1): 99–110.
Published Online: 20 March 2014
... for appropriate markers supporting clinical decision-making. Methods: The RCC cell line A-498 was treated with the DNA methyltransferase inhibitor zebularine under low-cytotoxicity conditions. RNA chip analyses revealed several upregulated transcripts that were further validated by qPCR on 49 matched pairs...