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Keywords: DNA methylation
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Journal Articles
Journal:
Urologia Internationalis
Urol Int (2023) 107 (5): 517–525.
Published Online: 23 May 2023
...Jinfeng Wu; Yongbao Wei; Tao Li; Le Lin; Zesong Yang; Liefu Ye Introduction: DNA methylation regulates gene transcriptional functions in the pathogenesis of malignant diseases. In prostate cancer, several tumor suppressors are known to be tumor specifically methylated. Methods: In this study, 450K...
Journal Articles
Subject Area:
Further Areas
Javier C. Angulo, Jose I. Lopez, Juan F. Dorado, Manuel Sanchez-Chapado, Begoña Colas, Santiago Ropero
Journal:
Urologia Internationalis
Urol Int (2016) 97 (1): 16–25.
Published Online: 25 May 2016
... characterized by their DNA methylation profile, one at higher risk to develop BCR (p = 0.005). Multivariate analysis revealed patients in this cluster (HR 2.56), and high-risk patients (HR 4.34) according to D'Amico classification were independent predictors of BCR after prostatectomy. From the selected genes...
Journal Articles
Subject Area:
Further Areas
Journal:
Urologia Internationalis
Urol Int (2010) 85 (3): 347–354.
Published Online: 13 July 2010
... cancer tissues than in adjacent tissues. The methylation of hepaCAM exon 2 was related to hepaCAM expression in bladder cancer tissues. Conclusions: Downregulation of hepaCAM expression plays an important role in the tumorigenesis and development of bladder cancer. DNA methylation may be important...
