...Paul Ostri; Tom Bonnesen; Tove Nilsson; Cai Frimodt-Møller During a 2-year period, 37 patients with symptomatic metastatic prostatic cancer were included in a prospective randomized phase-III trial. Nineteen patients were randomized to subcapsular orchiectomy, and 18 to cyproterone acetate (CPA...

...H. Becker; B. Düsterberg; H. Klosterhalfen Cyproterone acetate was administered orally and intramuscularly to 5 male patients. The level of the active substance in plasma was monitored at intervals during the period of application using radioimmunoassay specific for cyproterone acetate. The areas...

...U. Tunn; T. Senge; B. Schenck; F. Neumann The effect of 3α-androstanediol (3α-diol), 17β-estradiol (E 2 ) and cyproterone acetate (CA) on prostates in castrated beagle dogs were investigated by histologjcal and histochemical examinations. A significant increase of prostatic weight occurred after 6...