... difference exists between GAG excretion in healthy persons and in Ca-oxalate-stone patients. GAG excretion is diet-dependent and declines under conditions of balanced standardized diet. Evidence was obtained to show that GAG excretion follows a circadian rhythm with maximum during the day and minimum during...

... < 0.001). A statistically validated circadian rhythm in urinary concentration of GAGs was demonstrated in both the groups. However, the amplitude-acrophase test revealed a significant difference between the two groups (F 2,57 = 8.305; p < 0.001); the amplitude was 2.354 µmol/l in patients...

... in the 24-hour urine and its circadian rhythm were determined at 3-hour intervals using a new method of high performance liquid chromatography determination. This method also provides a means of monitoring the effectiveness of allopurinol therapy. 17 11 1987 17 12 1987 29 1 2010 © 1988...