... autophagy and promotes apoptosis of the prostate after castration. Methods: Thirty-six male SD rats were randomly divided into 3 groups ( n = 12): control group (sham operation), castration group, and HCQ group (castrated and treated with HCQ). On day 7, all mice were executed and prostates were isolated...

...John Lascaratos; Athanasios Kostakopoulos The authors present and comment on the surgical methods performed on hermaphrodites and for castration, which are unique in the medical bibliography of Byzantium and were described by the famous physician of the 7th century, Paul of Aegina. The latter...

...R. Stiens; B. Helpap The rat prostate was used to investigate cell loss (numeric atrophy) and altered cell proliferation after castration. Cell loss was determined by the proportion of apoptotic bodies. The apoptotic index was considerable and reached a maximum in the coagulating gland on day 2...

...Winston D. Edwards; John A. Thomas The effect of testosterone propionate (TP) pellets (15 mg) and/or prolactin (50 IU/kg body weight daily × 5 i.p.) on the morphology of ventral prostates transplanted to the cleared 5th mammary fat pads of intact or castrated male hosts or into intact...

...Cengiz Mordeniz; Ayhan Verit Aim: In the earliest records of human religion, castration was regarded as an act of devotion. Moreover, the ritual of circumcision is still followed by many modern religions. In this article, we have exposed the archeological, historical, cultural and religious...

...Yoshihiro Wada; Tomohiro Kuwahara; Wataru Takahashi; Masaki Yoshida; Hitoshi Iwashita; Shoichi Ueda Background: The effects of castration on nitric oxide- mediated relaxations and nitric oxide synthase activity in male rat corpus cavernosum smooth muscles. Methods: Eight-week-old male rats were...

... bicalutamide (50 mg once daily) plus either goserelin acetate or surgical castration for 48 weeks. Cox’s proportional hazard analysis was used to determine whether the decline of PSA following the use of this combination is predictive of a delay in progression. Results: PSA levels at weeks 4 and 12 were...