...Jiahua Pan; Wei Xue; Qi Chen; Yonghui Chen; Haige Chen; Yiran Huang Objectives: To evaluate the antifibrotic role of captopril during ureteral scarring in a New Zealand rabbit model. Materials and Methods: The tissue expression and the fluctuation of EGF, TGF-β, FN, Col Ia1, Col Ia2 and Col III...

...Masayoshi Yokoyama; Hidenobu Iwata; Kenji Ochi; Masafumi Takeuchi The effects of mannitol, methylprednisolone, furosemide, inosine, indomethacin and captopril on the recovery from hydronephrosis were examined in rat kidneys. After 1 week of ureteral obstruction, left ureterocystostomy was performed...

... role in this injury, we conducted this study to investigate whether administration of captopril reduced renal fibrosis in an experimental model using partial urethral obstruction (PUO) in neonatal dogs. Material and Methods: Experimental PUO was induced in all pups. These animals were then divided...