...Roohollah Sharifi; Larry Ojeda; Mary Lee In an open, prospective clinical trial, we evaluated the safety and efficacy of apalcillin in the treatment of complicated urinary tract infection. 21 hospitalized adult patients received apalcillin 2 g IV Q8-12h for 5–17 days. There were 8 upper tract...

...Mary Lee; Roohollah Sharifi Whereas impaired platelet aggregation is a well-known complication of penicillin usage, thrombocytopenia rarely occurs. We present the first case of apalcillin-induced thrombocytopenia and review the literature about this uncommon adverse effect of penicillins. © 1987...