...), and PSA doubling time (PSAdt), in patients with low-risk prostate cancer who are in an active surveillance (AS) program. Methods: An observational, retrospective, and longitudinal study of a sample of 86 patients included in AS program between January 2014 and October 2021 was conducted. A review...

... the quality of life. An alternative to surgery and radiotherapy treatments for low-risk PCa is active surveillance (AS), a strategy based on close disease monitoring and intervention only if the disease progresses. However, proper identification of low-risk PCa patients at the time of diagnosis is essential...

...Christian Wetterauer; Joel R. Federer-Gsponer; Francois D.J.P. Leboutte; Robin Mona; Jan Ebbing; Cyrill A. Rentsch; Lukas Manka; Hans H. Seifert; Stephen Wyler; Franz Recker; Maciej Kwiatkowski Introduction: Active surveillance (AS) strategies were established to avoid overtreatment of low-risk...

...Jan Herden; Andreas Schwarte; Edith A. Boedefeld; Lothar Weissbach Introduction: Optimal treatment for incidental prostate cancer (IPC) after surgical treatment for benign prostate obstruction is still debatable. We report on long-term outcomes of IPC patients managed with active surveillance...

...Tobias Steinwender; Lukas Manka; Mircea Grindei; Zhe Tian; Alexander Winter; Holger Gerullis; Pierre I. Karakiewicz; Peter Hammerer; Jonas Schiffmann Objective: The aim of this study was to examine elastography-based prostate biopsy in prostate cancer (PCa) patients under active surveillance...

...Juhyun Park; Sangjun Yoo; Min Chul Cho; Chang Wook Jeong; Ja Hyeon Ku; Cheol Kwak; Hyeon Hoe Kim; Hyeon Jeong Objective: The aim of this study was to evaluate the feasibility of including patients with biopsy Gleason score (bGS) 3 + 4 prostate cancer in an active surveillance (AS) protocol. Methods...

...Chung Un Lee; Si Hyun Sung; Chun Tae Jang; Minyong Kang; Hyun Hwan Sung; Byong Chang Jeong; Seong Il Seo; Seong Soo Jeon; Hyun Moo Lee; Hwang Gyun Jeon Objectives: We investigated the efficacy of transperineal template-guided mapping biopsy (TTMB) for patients on active surveillance (AS) or those...

... of confirmatory multiparametric magnetic resonance imaging (mpMRI) of the prostate at the time of Active Surveillance (AS) enrollment to reduce disease misclassification. Materials: From 2012 to 2016, 383 patients with low-risk disease respecting Prostate Cancer Research International AS criteria underwent...

... in multiparametric magnetic resonance imaging (mpMRI) plays an increasing role in the active surveillance (AS) of patients with low-risk prostate cancer (PCa). The aim of this study was to compare MRI/ultrasound-fusion biopsy (fusPbx) with systematic biopsy (sysPbx) in patients undergoing biopsy for AS. Methods...

... the criteria for Active Surveillance (AS), who elected to undergo immediate radical prostatectomy (RP). Material and Methods: Retrospective analysis including 1,212 patients with clinically localized prostate cancer (PCa) who met the eligibility criteria for AS. The primary outcomes were pathological upstaging...

.... Prostate cancer Radical prostatectomy Tumor upgrading Class risk Active surveillance Biology of the prostate depends on the endocrine system, which includes the hypothalamus, the pituitary gland, the adrenals, and testes. In the testis, Leydig interstitial cells are responsible...

... Artibani Objectives: To evaluate clinical factors associated with tumour upgrading (UPG) in low-intermediate risk patients who progressed while under active surveillance (AS) and underwent delayed radical prostatectomy. Material and Methods: The evaluated factors included prostate specific antigen (PSA...

... Objectives: To evaluate clinical predictors of disease reclassification or progression (DR/P) in prostate cancer patients elected to active surveillance (AS). Material and Methods: Patients were assessed on the basis of DR/P criteria. Predictors of DR/P were evaluated by multivariate logistic regression...

...) in patients with clinically localized prostate cancer (PCa) eligible for active surveillance (AS) according to Prostate Cancer Research International: Active Surveillance (PRIAS) criteria. Patients and Methods: We analyzed prospectively 73 patients with PCa and PRIAS criteria for low-risk disease. All...

... radical nephrectomy (RN) over nephron sparing surgery (NSS) as well as active surveillance (AS) over invasive treatment. Results: Three hundred six (7.4%) forms were included in our analysis. In patients with larger tumours (4 vs. 2 cm, OR 3.16), endophytic growth (endophytic vs. exophytic, OR 2.70...

...Jan Herden; Okyaz Eminaga; Sebastian Wille; Lothar Weissbach Objective: To report on a cohort of patients with incidental prostate cancer (IPC) that was treated by an active surveillance (AS) protocol in the HAROW study. Materials and Methods: The HAROW study is an observational study...

...Herbert Augustin; Katrin Mayerhofer; Maximilian Seles; Karl Pummer Background: Active surveillance (AS) represents an expectant treatment strategy for clinically localized prostate cancer (PCa) with low-risk features. Objective: The actual management as well as the pros and cons of AS were...

...Marco Randazzo; Josef Beatrice; Andreas Huber; Rainer Grobholz; Lukas Manka; Franz Recker; Maciej Kwiatkowski Introduction: Very low-risk prostate cancer (PCa) is being increasingly managed by active surveillance (AS). Our aim was to assess the influence of the origin of diagnosis on PCa...

...-confined versus non-organ-confined). Patients and Methods: This is a retrospective analysis of 165 men after radical prostatectomy fulfilling our active surveillance criteria at the time of surgery. Nominal variables were compared using Fisher's exact test, continuous variables using Mann-Whitney test...

... and 0.081, respectively). Conclusions: In patients with low-volume GS3+4 PCa at biopsy, underestimation may be effectively avoided when we select patients with PSA <4.73 and % maximum cancer involvement on positive cores <15%. Prostate cancer Active surveillance Gleason score 3+4 Radical...