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Keywords: 5-Aminolevulinic acid
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Journal Articles
Fluorescence Cystoscopy following Intravesical Instillation of 5-Aminolevulinic Acid: A New Procedure with High Sensitivity for Detection of Hardly Visible Urothelial Neoplasias
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M. Kriegmair, H. Stepp, P. Steinbach, W. Lumper, A. Ehsan, H.G. Stepp, K. Rick, R. Knüchel, R. Baumgartner, A. Hofstetter
Journal:
Urologia Internationalis
Urol Int (1995) 55 (4): 190–196.
Published Online: 03 February 2010
... be missed during conventional endoscopy under white light. A new procedure is reported for the fluorescence detection of urothelial dysplasia and early bladder cancer. The method is based on intravesical application of 5-aminolevulinic acid (ALA). ALA if applied exogenously induces accumulation...
Journal Articles
Photodynamic Therapy of Prostate Cancer by Means of 5-Aminolevulinic Acid-Induced Protoporphyrin IX – In vivo Experiments on the Dunning Rat Tumor Model
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Dirk Zaak, Ronald Sroka, Susanne Stocker, Karl Bise, Michael Lein, Michael Höppner, Dominic Frimberger, Peter Schneede, Oliver Reich, Martin Kriegmair, Ruth Knüchel, Reinhold Baumgartner, Alfons Hofstetter
Journal:
Urologia Internationalis
Urol Int (2004) 72 (3): 196–202.
Published Online: 15 April 2004
... of prostate carcinoma (PCA), the aim of this study was to evaluate PDT by means of 5-aminolevulinic acid (5-ALA)-induced protoporphyrin IX (PPIX) in an in vivo tumor model. Methods: The model used was the Dunning R3327 tumor. First of all, the pharmacokinetics and the localization of PPIX were obtained using...
Journal Articles
No Generalized Skin Phototoxicity after Intravesical Application of 5-Aminolevulinic Acid for Fluorescence Diagnosis ofSuperficial Bladder Cancer
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Journal:
Urologia Internationalis
Urol Int (2000) 64 (3): 126–128.
Published Online: 02 June 2000
...T. Filbeck; M.B. Wimmershoff; U. Pichlmeier; S. Karrer; W.F. Wieland; R.-M. Szeimies; W. Rössler Introduction: A prospective monocenter open study was carried out to evaluate if generalized phototoxic skin reactions occur after intravesical application of 5-aminolevulinic acid (ALA...
Journal Articles
5-Aminolevulinic Acid-Induced Fluorescence Endoscopy for the Detection of Lower Urinary Tract Tumors
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Journal:
Urologia Internationalis
Urol Int (1999) 63 (1): 27–31.
Published Online: 03 December 1999
... and flat lesions such as carcinoma in situ is known to be difficult, and thus a source of recurrences. We report on the recent experience with the intravesical application of the photosensitizer prodrug 5-aminolevulinic acid (5-ALA), which is a nontoxic physiological heme substrate. Initial results from...