Background/Aims/Objectives: To report the outcome of staged urethroplasty with buccal mucosa and vascularised scrotal flap after failed hypospadias surgery. Methods:n = 35. Inclusion criteria: destroyed urethral plate, deficient local skin, fistula and penile deviation. Five out of 35 patients also had a secondary proximal stricture. Stage 1: excision of scarred tissue and fistulae, correction of the penile deviation through dorsal plication and the ventral placement and quilting of buccal graft. Stage 2: tubularisation of the neourethral plate; in 20 patients with deficient penile skin a vascularised scrotal flap was developed and transferred on the tubularised urethra. In 5 patients, the proximal stricture was repaired during a separate operation by using buccal graft, the distal urethra was marsupialised. The repair of the distal urethra was performed later as described above. Results: Thirty-three patients are recurrence-free without further interventions; successful reoperation was done in 2 cases. Complications: 1 graft necrosis; 1 coronary fistula; 1 scrotal flap necrosis and 1 case of hematoma. Conclusions: Complicated strictures after multiple failed hypospadias repair are well managed by using buccal graft. The vascularised scrotal flap is a very useful tool in case of deficient and scarred penile skin and could explain the low rate of fistula formation in our series.

1.
Swinney J: Urethroplasty: an assessment after seven years' experience. Br J Urol 1957;29:293-297.
2.
Singh O, Gupta SS, Arvind NK: Anterior urethral strictures: a brief review of the current surgical treatment. Urol Int 2011;86:1-10.
3.
Pansadoro V, Emiliozzi P, Gaffi M, et al: Buccal mucosa urethroplasty in the treatment of bulbar urethral strictures. Urology 2003;61:1008-1010.
4.
Andrich DE, Mundy AR: What is the best technique for urethroplasty? Eur Urol 2008;54:1031-1041.
5.
Yachia D: Modified corporoplasty for the treatment of penile curvature. J Urol 1990;143:80-82.
6.
Thomas DF: Hypospadiology: science and surgery. BJU Int 2004;93:470-473.
7.
Prat D, Natasha A, Polak A, et al: Surgical outcome of different types of primary hypospadias repair during three decades in a single center. Urology 2012;79:1350-1353.
8.
Manzoni G, Bracka A, Palminteri E, Marrocco G: Hypospadias surgery: when, what and by whom? BJU Int 2004;94:1188-1195.
9.
Myers JB, McAninch JW, Erickson BA, Breyer BN: Treatment of adults with complications from previous hypospadias surgery. J Urol 2012;188:459-463.
10.
Jayanthi VR, McLorie GA, Khoury AE, Churchill BM: Can previously relocated penile skin be successfully used for salvage hypospadias repair? J Urol 1994;152(2 pt 2):740-743; discussion 743.
11.
Simmons GR, Cain MP, Casale AJ, et al: Repair of hypospadias complications using the previously utilized urethral plate. Urology 1999;54:724-726.
12.
Borer JG, Bauer SB, Peters CA, et al: Tubularized incised plate urethroplasty: expanded use in primary and repeat surgery for hypospadias. J Urol 2001;165:581-585.
13.
Snodgrass WT: Tubularized incised plate (TIP) hypospadias repair. Urol Clin North Am 2002;29:285-290, v.
14.
Emir L, Germiyanoglu C, Erol D: Onlay island flap urethroplasty: a comparative analysis of primary versus reoperative cases. Urology 2003;61:216-219; discussion 219.
15.
Bürger RA, Müller SC, el-Damanhoury H, et al: The buccal mucosal graft for urethral reconstruction: a preliminary report. J Urol 1992;147:662-664.
16.
Ding J, Li Q, Li S, et al: Ten years' experience for hypospadias repair: combined buccal mucosa graft and local flap for urethral reconstruction. Urol Int 2014;93:454-459.
17.
Fichtner J, Filipas D, Fisch M, et al: Long-term follow-up of buccal mucosa onlay graft for hypospadias repair: analysis of complications. J Urol 2004;172(5 pt 1):1970-1972; discussion 1972.
18.
Metro MJ, Wu HY, Snyder HM 3rd, et al: Buccal mucosal grafts: lessons learned from an 8-year experience. J Urol 2001;166:1459-1461.
19.
Secrest CL: Staged urethroplasty: indications and techniques. Urol Clin North Am 2002;29:467-475, viii-ix.
20.
Bracka A: A versatile two-stage hypospadias repair. Br J Plast Surg 1995;48:345-352.
21.
Snodgrass W, Elmore J: Initial experience with staged buccal graft (bracka) hypospadias reoperations. J Urol 2004;172(4 pt 2):1720-1724; discussion 1724.
22.
Barbagli G, De Angelis M, Palminteri E, Lazzeri M: Failed hypospadias repair presenting in adults. Eur Urol 2006;49:887-894; discussion 895.
23.
Greenwell TJ, Venn SN, Mundy AR: Changing practice in anterior urethroplasty. BJU Int 1999;83:631-635.
24.
Leslie B, Lorenzo AJ, Figueroa V, et al: Critical outcome analysis of staged buccal mucosa graft urethroplasty for prior failed hypospadias repair in children. J Urol 2011;185:1077-1082.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.