Introduction: Transurethral resection risks excessive absorption of irrigating fluid with potentially severe or life-threatening consequences. We determined the amount of absorbed saline irrigation fluid during photoselective vaporisation of the prostate (PVP) and bipolar transurethral resection of the prostate (bTURP). Patients and Methods: Patients at our institution treated by one of these methods were monitored by the alcometric method: ethanol is added to the irrigation fluid and blood alcohol is measured with a breathalyser. Various possible correlations were investigated. Results: Data from 71 patients (36 PVP, 35 bTURP) were analysed. Detection of any absorption was more frequent under bTURP (71% of patients) than under PVP (39%; p = 0.006). Absorption in the volume range 500-1,000 ml was conspicuously more frequent in the bTURP procedure than in PVP. Conclusions: Presence of absorption was more frequent under bTURP than under PVP. However, high-volume absorption was more frequent during bTURP than in PVP.

1.
Berges RR, Pientka L: Management of the BPH syndrome in Germany: who is treated and how? Eur Urol 1999;36(suppl 3):21-27.
2.
Wein AJ: Campbell-Walsh Urology, ed 9. Philadelphia, Saunders, Elsevier, 2007, vol 3, p 2846.
3.
Gratzke C, Bachmann A, Descazeaud A, Drake MJ, Madersbacher S, Mamoulakis C, Oelke M, Tikkinen KA, Gravas S: EAU guidelines on the assessment of non-neurogenic male lower urinary tract symptoms including benign prostatic obstruction. Eur Urol 2015;67:1099-1109.
4.
Hahn RG: Fluid absorption and the ethanol monitoring method. Acta Anaesthesiol Scand 2015;59:1081-1093.
5.
Hahn RG: The use of ethanol to monitor fluid absorption during transurethral resection of the prostate. Scand J Urol Nephrol 1999;33:277-283.
6.
Gehring H: Die Messung der Atem-Alkohol-Konzentration als Monitoring der Einschwemmung von Spülflüssigkeit Während Endourologischer Eingriffe. Klinische Bedeutung und Technische Anforderungen. Lengerich, Pabst, 1998.
7.
Gehring H, Nahm W, Baerwald J, Fornara P, Schneeweiss A, Roth-Isigkeit A, Schmucker P: Irrigation fluid absorption during transurethral resection of the prostate: spinal vs. general anaesthesia. Acta Anaesthesiol Scand 1999;43:458-463.
8.
Hermanns T, Grossmann NC, Wettstein MS, Fankhauser CD, Capol JC, Poyet C, Hefermehl LJ, Zimmermann M, Sulser T, Müller A: Absorption of irrigation fluid occurs frequently during high power 532 nm laser vaporization of the prostate. J Urol 2015;193:211-216.
9.
Barber NJ, Zhu G, Donohue JF, Thompson PM, Walsh K, Muir GH: Use of expired breath ethanol measurements in evaluation of irrigant absorption during high-power potassium titanyl phosphate laser vaporization of prostate. Urology 2006;67:80-83.
10.
Hahn RG: Early detection of the TUR syndrome by marking the irrigating fluid with 1% ethanol. Acta Anaesthesiol Scand 1989;33:146-151.
11.
Hahn RG: The transurethral resection syndrome. Acta Anaesthesiol Scand 1991;35:557-567.
12.
Rassweiler J, Teber D, Kuntz R, Hofmann R: Complications of transurethral resection of the prostate (TURP) - incidence, management, and prevention. Eur Urol 2006;50:969-979; discussion 980.
13.
Jonas U, Gabouev AI, Herrmann TR, Höfner K, Michel MC, Alschibaja M, Hartung R: [Benign prostate hyperplasia]. Urologe A 2006;45(suppl 4):134-144.
14.
Hermanns T, Fankhauser CD, Hefermehl LJ, Kranzbühler B, Wong LM, Capol JC, Zimmermann M, Sulser T, Müller A: Prospective evaluation of irrigation fluid absorption during pure transurethral bipolar plasma vaporisation of the prostate using expired-breath ethanol measurements. BJU Int 2013;112:647-654.
15.
Kessling C, Schwitalla S: [Experiences with routine monitoring of ethanol concentration in expired air in transurethral prostate resection]. Anaesthesiol Reanim 2000;25:96-101.
16.
Heinrich E, Schiefelbein F, Schoen G: Technique and short-term outcome of green light laser (KTP, 80W) vaporisation of the prostate. Eur Urol 2007;52:1632-1637.
17.
Kuo RL, Paterson RF, Kim SC, Siqueira TM Jr, Elhilali MM, Lingeman JE: Holmium laser enucleation of the prostate (HoLEP): a technical update. World J Surg Oncol 2003;1:6.
18.
Bachmann A, Tubaro A, Barber N, d'Ancona F, Muir G, Witzsch U, Grimm MO, Benejam J, Stolzenburg JU, Riddick A, Pahernik S, Roelink H, Ameye F, Saussine C, Bruyère F, Loidl W, Larner T, Gogoi NK, Hindley R, Muschter R, Thorpe A, Shrotri N, Graham S, Hamann M, Miller K, Schostak M, Capitán C, Knispel H, Thomas JA: A European multicenter randomized noninferiority trial comparing 180 W GreenLight XPS laser vaporization and transurethral resection of the prostate for the treatment of benign prostatic obstruction: 12-month results of the GOLIATH study. J Urol 2015;193:570-578.
19.
Hahn RG: Ethanol monitoring of irrigating fluid absorption in transurethral prostatic surgery. Anesthesiology 1988;68:867-873.
20.
Hultén JO, Jorfeldt LS, Wictorsson YM: Monitoring fluid absorption during TURP by marking the irrigating solution with ethanol. Scand J Urol Nephrol 1986;20:245-251.
21.
Scherhag A, Elich D, Heinrichs W: [Continuous breath alcohol analysis. Monitoring of irrigation absorption syndrome in transurethral prostate resection]. Anaesthesist 1995;44:436-441.
22.
Zink M, Waltensdorfer A, Lampel A, Rath M, Lipsky H, Engler J: [Calculation of lavage volume in transurethral prostate resection (TURP)]. Anasthesiol Intensivmed Notfallmed Schmerzther 1997;32:219-225.
23.
Hahn RG: Monitoring of TURP with ethanol. Lancet 1991;338:1602.
24.
Dripps RD: New classification of physical status. Anesthesiol 1963;24:111.
25.
Broggi E, May A, Giretti G, Tabchouri N, Lorphelin H, Brichart N, Bruyère F: Long-term outcomes of 80-watt KTP and 120-watt HPS GreenLight photoselective vaporization of the prostate. Urol Int 2014;93:229-236.
26.
Fang K, Yang B, Qu R, Dong Q: [Effect and safety of GreenLight HPS 120-W laser vaporization of the prostate for different benign prostatic hyperplasia populations]. Zhonghua Nan Ke Xue 2015;21:619-625.
27.
Thomas JA, Tubaro A, Barber N, d'Ancona F, Muir G, Witzsch U, Grimm MO, Benejam J, Stolzenburg JU, Riddick A, Pahernik S, Roelink H, Ameye F, Saussine C, Bruyère F, Loidl W, Larner T, Gogoi NK, Hindley R, Muschter R, Thorpe A, Shrotri N, Graham S, Hamann M, Miller K, Schostak M, Capitán C, Knispel H, Bachmann A: A multicenter randomized noninferiority trial comparing GreenLight-XPS laser vaporization of the prostate and transurethral resection of the prostate for the treatment of benign prostatic obstruction: two-yr outcomes of the GOLIATH study. Eur Urol 2016;69:94-102.
28.
Hahn RG, Resby M: Volume kinetics of Ringer's solution and dextran 3% during induction of spinal anaesthesia for caesarean section. Can J Anaesth 1998;45(5 pt 1):443-451.
29.
Hahn RG: Prevention of TUR syndrome by detection of trace ethanol in the expired breath. Anaesthesia 1990;45:577-581.
30.
Hahn RG, Shemais H, Essén P: Glycine 1.0% versus glycine 1.5% as irrigating fluid during transurethral resection of the prostate. Br J Urol 1997;79:394-400.
31.
Balzarro M, Ficarra V, Bartoloni A, Tallarigo C, Malossini G: The pathophysiology, diagnosis and therapy of the transurethral resection of the prostate syndrome. Urol Int 2001;66:121-126.
32.
Hahn RG, Sandfeldt L, Nyman CR: Double-blind randomized study of symptoms associated with absorption of glycine 1.5% or mannitol 3% during transurethral resection of the prostate. J Urol 1998;160:397-401.
33.
Hahn RG: Trapping of electrolytes during fluid absorption in transurethral resection of the prostate. Scand J Urol Nephrol 1997;31:259-263.
34.
Baumunk D, Strang CM, Kropf S, Schäfer M, Schrader M, Weikert S, Cash H, Breckwoldt J, Miller K, Hachenberg T, Schostak M: Impact of thoracic epidural analgesia on blood loss in radical retropubic prostatectomy. Urol Int 2014;93:193-201.
35.
Hahn RG: The volumetric fluid balance as a measure of fluid absorption during transurethral resection of the prostate. Eur J Anaesthesiol 2000;17:559-565.
36.
Shipstone DP, Inman RD, Beacock CJ, Coppinger SW: Validation of the ethanol breath test and on-table weighing to measure irrigating fluid absorption during transurethral prostatectomy. BJU Int 2002;90:872-875.
37.
Hjertberg H, Ekberg S, Hahn R, Hultén J, Jorfeldt L, Svedberg J: Absorption of irrigating fluid during transurethral prostatic resection as measured by ethanol, radioisotopes, and regular-interval monitoring. Urology 1991;38:417-422.
38.
Drobin D, Hjelmqvist H, Piros D, Hahn RG: Monitoring of fluid absorption with nitrous oxide during transurethral resection of the prostate. Acta Anaesthesiol Scand 2008;52:509-513.
39.
Piros D, Fagerström T, Collins JW, Hahn RG: Glucose as a marker of fluid absorption in bipolar transurethral surgery. Anesth Analg 2009;109:1850-1855.
40.
Hahn RG, Ekengren JC: Patterns of irrigating fluid absorption during transurethral resection of the prostate as indicated by ethanol. J Urol 1993;149:502-506.
41.
Widmark E: Die Theoretischen Grundlagen und die Praktische Verwendbarkeit der Gerichtlich-Medizinischen Alkoholbestimmung. Berlin, Wien, Urban und Schwarzenberg, 1932.
42.
Rangno RE, Kreeft JH, Sitar DS: Ethanol ‘dose-dependent' elimination: Michaelis-Menten v classical kinetic analysis. Br J Clin Pharmacol 1981;12:667-673.
43.
Rancke F, Schmeller N, Albrecht M: [The addition of ethyl alcohol to the irrigating fluid. Monitoring fluid absorption during transurethral resection of the prostate]. Anaesthesist 1992;41:324-330.
44.
Hahn RG: Calculation of irrigant absorption by measurement of breath alcohol level during transurethral resection of the prostate. Br J Urol 1991;68:390-393.
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