Objective: To compare safety and effectiveness of flexible ureteroscopy (F-URS) and laparoscopic retroperitoneal ureterolithotomy (L-RU) in treatment of proximal ureteral stones larger than 15 mm. Materials and Methods: This study included 103 patients treated with L-RU (Group I), and 80 patients treated with F-URS (Group II) due to proximal ureteral stones larger than 1.5 cm, in a single center. Patients' characteristics and procedure-related parameters including success rate, operation time, hospital stay, postoperative visual analogue scale (VAS) scores, auxiliary procedures, and complications were compared between Groups I and II. Results: It was seen that both methods were effective in the treatment of large ureteral stones; however, R-LU provided a higher stone-free rate (100 vs. 87.5%), a lower complication rate (10.6 vs. 23.7%), and a shorter operation time (65.4 vs. 75.1 min). On the other hand, patients treated with F-URS had less postoperative pain, a shorter hospital stay, a faster return to daily activities. Conclusions: For treatment of large proximal ureteral stones, L-RU provides significantly higher success and lower retreatment rate compared with F-URS. Our results also indicate that R-LU, which has been regarded as an invasive procedure is not as invasive as it is thought to be, and it must be kept in mind that F-URS may cause complications despite its noninvasive nature.

1.
Lopes Neto AC, Korkes F, Silva JL 2nd, et al: Prospective randomized study of treatment of large proximal ureteral stones: extracorporeal shock wave lithotripsy versus ureterolithotripsy versus laparoscopy. J Urol 2012;187:164-168.
2.
Fang YQ, Qiu JG, Wang DJ, et al: Comparative study on ureteroscopic lithotripsy and laparoscopic ureterolithotomy for treatment of unilateral upper ureteral stones. Acta Cir Bras 2012;27:266-270.
3.
Wang Y, Hou J, Wen D, et al: Comparative analysis of upper ureteral stones (> 15 mm) treated with retroperitoneoscopic ureterolithotomy and ureteroscopic pneumatic lithotripsy. Int Urol Nephrol 2010;42:897-901.
4.
Sun X, Xia S, Lu J, et al: Treatment of large impacted proximal ureteral stones: randomized comparison of percutaneous antegrade ureterolithotripsy versus retrograde ureterolithotripsy. J Endourol 2008;22:913-917.
5.
Resorlu B, Unsal A, Gulec H, et al: A new scoring system for predicting stone-free rate after retrograde intrarenal surgery: the ‘Resorlu-Unsal stone score'. Urology 2012;80:512-518.
6.
Bozkurt OF, Resorlu B, Yildiz Y, et al: Retrograde intrarenal surgery versus percutaneous nephrolithotomy in the management of lower-pole renal stones with a diameter of 15 to 20 mm. J Endourol 2011;25:1131-1135.
7.
Breda A, Ogunyemi O, Leppert JT, et al: Flexible ureteroscopy and laser lithotripsy for single intrarenal stones 2 cm or greater - is this the new frontier? J Urol 2008;179:981-984.
8.
Riley JM, Stearman L, Troxel S: Retrograde ureteroscopy for renal stones larger than 2.5 cm. J Endourol 2009;23:1395-1398.
9.
Tefekli A, Ali Karadag M, Tepeler K, et al: Classification of percutaneous nephrolithotomy complications using the modified Clavien grading system: looking for a standard. Eur Urol 2008;53:184-190.
10.
Nabi G, Baldo O, Cartledge J, et al: The impact of the dornier compact delta lithotriptor on the management of primary ureteric calculi. Eur Urol 2003;44:482-486.
11.
Park H, Park M, Park T: Two-year experience with ureteral stones: extracorporeal shockwave lithotripsy v ureteroscopic manipulation. J Endourol 1998;12:501-504.
12.
Simunovic D, Sudarevic B, Galic J: Extracorporeal shockwave lithotripsy in elderly: impact of age and comorbidity on stone-free rate and complications. J Endourol 2010;24:1831-1837.
13.
Topaloglu H, Karakoyunlu N, Sari S, et al: A comparison of antegrade percutaneous and laparoscopic approaches in the treatment of proximal ureteral stones. Biomed Res Int 2014;2014:691946.
14.
Kumar V, Ahlawat R, Banjeree GK, et al: Percutaneous ureterolitholapaxy: the best bet to clear large bulk impacted upper ureteral calculi. Arch Esp Urol 1996;49:86-91.
15.
Goel R, Aron M, Kesarwani PK, et al: Percutaneous antegrade removal of impacted upper-ureteral calculi: still the treatment of choice in developing countries. J Endourol 2005;19:54-57.
16.
Long Q, Guo J, Xu Z, et al: Experience of mini-percutaneous nephrolithotomy in the treatment of large impacted proximal ureteral stones. Urol Int 2013;90:384-388.
17.
Michel MS, Trojan L, Rassweiler JJ: Complications in percutaneous nephrolithotomy. Eur Urol 2007;51:899-906.
18.
Karadag MA, Demir A, Cecen K, et al: Flexible ureterorenoscopy versus semirigid ureteroscopy for the treatment of proximal ureteral stones: a retrospective comparative analysis of 124 patients. Urol J 2014;11:1867-1872.
19.
Zhu H, Ye X, Xiao X, et al: Retrograde, antegrade, and laparoscopic approaches to the management of large upper ureteral stones after shockwave lithotripsy failure: a four-year retrospective study. J Endourol 2014;28:100-103.
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