From the late 15th century onwards, cutting for stones in patients' heads to cure mental illness was depicted in European art. The earliest and most famous painting of this kind is The Cure of Folly, painted by Jheronimus Bosch around the turn of the 15th to the 16th century. In general, these depictions are thought to relate to surgical as well as mental health practices of that time. However, it can be questioned whether barber surgeons or quacks cut for stones in patients' heads, and if they did not, what the meaning of Bosch's and other artists' paintings might be. Paintings from the 15th to 17th centuries and historical sources from the history of medicine as well as art history served as a basis for this contribution. The combination of sources from the histories of urology and psychiatry opens a new perspective on depictions of cranial lithotomy. Taking this into account, it does not seem likely that surgeons or quacks cut for cranial stones in early modern Europe. Few therapy options existed to effectively treat mental problems, and, hence, most interpretations of Bosch's picture point to the gullibility of patients as its central theme. At the same time, the depictions of cranial lithotomy may illustrate the limits of the medical profession and an abstract hope for successful psychosurgery analogous to the surgical removal of stones from the urinary tract.

1.
Verboom HJ: Jheronimus Bosch en de chirurg: Interpretaties van De Keisnijding bezien vanuit de middeleeuwse medische praktijk. Heerlen, Open Universiteit Nederland, 2011.
2.
Southgate T: The Cure of Folly(Extraction of the Stone of Madness). JAMA 2003;289:13.
3.
Gross CG: ‘Psychosurgery' in Renaissance art. Trends Neurosci 1999;22:429-431.
4.
Harris JC: The Cure of Folly. Arch Gen Psychiatry 2004;61:1187.
5.
Salcman M: The Cure of Folly or The Operation for the Stone by Hieronymus Bosch (c. 1450-1516). Neurosurgery 2006;59:935-937.
6.
Hauri D: Die Steinschneider: Eine Kulturgeschichte menschlichen Leidens und ärztlicher Kunst. Berlin, Springer, 2013.
7.
Murphy LJT: The History of Urology. Springfield, Thomas, 1972.
8.
Sachs M: Geschichte der operativen Chirurgie. Heidelberg, Kaden, 2000, vol 1: Historische Entwicklung chirurgischer Operationen.
9.
Wangensteen OH, Wangensteen SD: The Rise of Surgery: From Empiric Craft to Scientific Discipline. Folkestone, Dawson Publishing, 1978.
10.
Hayward R: Medicine and the mind; in Jackson M (ed): The Oxford Handbook of the History of Medicine. Oxford, Oxford UP, 2011, pp 524-542.
11.
Shorter E: A History of Psychiatry: From the Era of the Asylum to the Age of Prozac. New York, Wiley, 1997.
12.
Sachs M: Geschichte der operativen Chirurgie: Ergänzungs- und Registerband. Heidelberg, Kaden, 2005.
13.
Valenstein E: History of psychosurgery; in Greenblatt SH, Dagi TF, Epstein MH (eds): A History of Neurosurgery in Its Scientific and Professional Contexts. New York, Thieme, 1997, pp 499-516.
14.
Dixon L: Bosch. London, Phaidon, 2003.
15.
Dixon L: Bosch's Stone Operation: meaning, medicine, and morality. Hektoen Int J Med Humanit 2010;2. http://www.hektoeninternational.org/Boschsstoneoperation.html.
16.
Schupbach W: A new look at The Cure of Folly. Med Hist 1978;22:267-281.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.