Aim: To compare the bladder dysfunction associated with benign prostatic enlargement (BPE) in patients with and without diabetes mellitus (DM) by urodynamic study. Materials and Methods: The records of 166 first-visit BPE patients were reviewed. Patients were divided into two groups: concomitant group (CG) – 74 patients with BPE complicated with DM, and single group (SG) – 92 isolated BPE patients. Urodynamic findings of the two groups were analyzed. Results: In the clinical data, increased postvoiding residual urine volume (PVR) appeared more often in CG (p < 0.05). In the urodynamic findings, significantly higher maximum cystometric capacity (MCC), incidence of impaired bladder sensation, bladder compliance and detrusor overactivity existed in CG (p < 0.05). In addition, the maximum detrusor pressure during voiding (Pdetmax) and the incidence of bladder outlet obstruction (BOO) were significantly higher in SG (p < 0.05). Conclusions: Impaired bladder function is more severe in patients with BPE complicated with DM than those isolated BPE patients. Urodynamic study can provide objective data on diagnosis of voiding dysfunction in BPE patients with and without DM, and it is helpful for doctors to choose better clinical intervention.

Keywords:
Diabetes mellitus, Urodynamic study, Prostatic hyperplasia, Bladder dysfunction
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© 2008 S. Karger AG, Basel
2008
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