In this paper a method of semiquantitative cysteine determination is presented, which is based on the formation of a red cysteine-Na-nitroprusside salt. The method is a suitable rapid test for checking the process of ascorbic acid therapy in cystinuria and cystine urolithiasis patients. It guarantees acceptable reproducibility of values and can be easily carried out in every clinicochemical laboratory. With the K2CO3/nitroprusside test described and an additional cystine rapid test (Ni2+/S2O42–– tablet reagency) a separate semiquantitative differentiation of cysteine and cystine in fresh (!) urine is possible.

Keywords:
Cystine urolithiasis, Ascorbic acid therapy, Cysteine/cystine rapid tests
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© 1987 S. Karger AG, Basel
1987
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