Xanthogranulomatous pyelonephritis is a rather peculiar and rare form of chronic pyelonephritis and is usually caused by calculous urinary tract obstruction. The characteristic pathological finding is the presence of foam cells. We present 2 cases and give special attention to the clinical diagnosis and the phenomenon of nephrogenic hepatic dysfunction. A new series of 200 cases has been analyzed, and the most typical features of this inflammatory condition are compared with the findings in earlier series from the world literature.

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