The healing of 95 end-to-end anastomoses of the middle part of the ureter was studied in 52 dogs. The anastomosis was made with the following methods. In the first series the American vascular stapler was used, in three other series the anastomosis was made with interrupted sutures of medium chronic catgut, Prolene and Dexon, respectively. The results were, in particular in the first 2 weeks, in favour of the American vascular stapler, shown among others by the slight increase of the urea and creatinine levels. This increase appeared to be not significantly different from the values observed in a control series in which only unilateral nephrectomy was performed. The registration of ureter-electropotentials showed distinct conduction from the proximal to the distal part if metal staples were used. Histological examination showed that the ideal adaptation obtained with the AVS promoted the primary healing of the anastomosis, among others by the rapid covering of the defect with migrating epithelial cells. The results of histochemical staining of the anastomoses were negative in view of polymucosaccharides.

Keywords:
Ureter, Experimental surgery, Experimental urology, Wound-healing electrophysiology, Suture material
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© 1973 S. Karger AG, Basel
1973
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