The experimental procedure is based on Trendelenburg’s apparatus. 39 human upper, middle and lower ureter segments have been studied. Upper and lower segments showed typical differences of peristalsis during spontaneous activity as to frequency, muscle contraction and increase in pressure in the lumen. Electric potentials preceded mechanical alterations in all cases at 0.1 sec. The upper ureter showed a relation of increase in pressure in the lumen and in frequency. Activity in the lower parts seemed to be relatively constant. The frequency in the electromyogram of the ureter could be influenced by sympathetically acting drugs. Parasympathetically acting drugs had no effect in these experiments. α-Receptor stimulation caused an increase in the diastolic tonus of the ureter as well as in its frequency and its systolic retraction with a higher pressure in its lumen. Prevailing of β-receptors had a negative chronotropic effect.

Keywords:
Human ureter dependence on drugs dependence on pressure
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© 1973 S. Karger AG, Basel
1973
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