Continuing renal function following total obstruction of the ureter is possible because of continuous re-absorption from the renal pelvis via lymph and/or blood vessels. The reabsorption of various substances with low as well as high molecular weight, and even of bacteria has been demonstrated. To find out whether this reabsorption mechanism depends upon physical or chemical properties 10 substances with various molecular weights injected into the totally occluded renal pelvis were compared directly in 14 dogs. The concentration of these substances were followed in urine, renal vein, renal hilar lymph and artery. It was found that all substances, even colloids were absorbed at identical rates regardless of physical and chemical properties. A pyelovenous as well as a pyelolymphatic pathway, simultaneously active, could be demonstrated.

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