The authors present a case of Monilium albicans of the urinary bladder with a review of the pathogenesis and treatment. We consider the bladder infection to be a result of a vulvo-vaginal or anal infection. The lesion may present thrush-like lesions which produce pseudo membranous cystitis, or soft globules – grey or yellow in color, which can be easily voided or aspirated from the bladder. The cystographic appeance is a typical ‘swiss cheese’ shadow which may be falsely interpreted as multiple tumors. The bacteriologist makes the diagnosis by using Sabouraud’s dextrose agar medium. The disease was seen exclusively in diabetics, practically all of them females, 89% of whom had been on antibiotics. The authors conclude that patients with diabetes, recurrent urinary tract infections and persistent vaginal moniliasis should have their urine cultured on Sabouraud’s media. It is much easier to treat the disease in its early phase than later when the Monilium albicans involves the entire wall, or when it fills the bladder with small fungus balls.

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