Studying the properties of the urinary leucocytes the authors have revealed that Sternheimer-Malbin cells (the S.-M. cells) are not always found in the urine of the patients with pyelonephritis. The cells are formed in the urine out of ‘live’, active leucocytes only in certain states of the osmotic pressure of the urine and osmotic resistance of the leucocytes. Active leucocytes are found in the urine provided that there is an active inflammatory process occuring only in the renal parenchyma, and they can be easily detected by reduction of the osmotic pressure of the urine. The technique of detection of active leucocytes in the urine is presented. The suggested method of investigation is of great value in diagnosis of acute and especially of chronic pyelonephritis, as it enables one to distinguish pyuria in pyelonephritis and pyuria resulting from cystitis. The analysis of the urinary sediment for active leucocytes content was carried out in 365 patients with inflammatory-suppurative diseases of the kidneys and the urinary bladder. The analysis of the urinary sediment in 77 patients with acute pyelonephritis has revealed active leucocytes in 74 patients (96.1%), whereas out of 163 patients with chronic pyelonephritis they were found in 139 patients (84.5%). None of 95 patients with acute and chronic cystitis was found to have active leucocytes in the urine.

This content is only available via PDF.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.