We report 2 cases of de novo renal cell carcinoma (RCC) in renal grafts after transplantation. Both patients underwent nephron sparing surgery (NSS) 211 and 167 months after transplantation, revealing papillary RCC with a tumour size >4 cm (pT1a). Within a follow-up of 25 and 32 months after NSS, a stable renal function without indication for dialysis was present. No recurrence of RCC in both cases was reported within the yearly routine examinations. NSS in kidney allografts is a safe procedure with preservation of renal function.

1.
Doublet
JD
,
Peraldi
MN
,
Gattegno
B
,
Thibault
P
,
Sraer
JD
.
Renal cell carcinoma of native kidneys: prospective study of 129 renal transplant patients
.
J Urol
.
1997 Jul
;
158
(
1
):
42
4
.
2.
Penn
I
.
Primary kidney tumors before and after renal transplantation
.
Transplantation
.
1995 Feb
;
59
(
4
):
480
5
.
3.
Tillou
X
,
Doerfler
A
,
Collon
S
,
Kleinclauss
F
,
Patard
JJ
,
Badet
L
, et al.
De novo kidney graft tumors: results from a multicentric retrospective national study
.
Am J Transplant
.
2012 Dec
;
12
(
12
):
3308
15
.
4.
Barama
A
,
St-Louis
G
,
Nicolet
V
,
Hadjeres
R
,
Daloze
P
.
Renal cell carcinoma in kidney allografts: a case series from a single center
.
Am J Transplant
.
2005 Dec
;
5
(
12
):
3015
8
.
5.
Tillou
X
,
Guleryuz
K
,
Doer
,
er
A
,
Bensadoun
H
,
Chambade
D
, et al.
Nephron sparing surgery for de novo kidney graft tumor: results from a multicentre national study
.
Am J Transplant
.
2014 Sep
;
14
(
9
):
2120
5
.
6.
Karami
S
,
Yanik
EL
,
Moore
LE
,
Pfeiffer
RM
,
Copeland
G
,
Gonsalves
L
, et al.
Risk of renal cell carcinoma among kidney transplant recipients in the United States
.
Am J Transplant
.
2016 Dec
;
16
(
12
):
3479
89
.
7.
Mehrazin
R
,
Smaldone
MC
,
Egleston
B
,
Tomaszewski
JJ
,
Concodora
CW
,
Ito
TK
, et al.
Is anatomic complexity associated with renal tumor growth kinetics under active surveillance?
Urol Oncol
.
2015 Apr
;
33
(
4
):
167
.
8.
Ljungberg
B
,
Albiges
L
,
Abu-Ghanem
Y
,
Bensalah
K
,
Dabestani
S
,
Fernández-Pello
S
, et al.
European association of urology guidelines on renal cell carcinoma: the 2019 update
.
Eur Urol
.
2019 May
;
75
(
5
):
799
810
.
9.
Kitagawa
Y
,
Nakashima
K
,
Shima
T
,
Izumi
K
,
Narimoto
K
,
Miwa
S
, et al.
Clinicopathological outcomes of clinical T1a renal cell carcinoma by tumor size
.
Jpn J Clin Oncol
.
2011 May
;
41
(
5
):
637
41
.
10.
Kaouk
JH
,
Spana
G
,
Hillyer
SP
,
White
MA
,
Haber
GP
,
Goldfarb
D
.
Robotic-assisted laparoscopic partial nephrectomy for a 7-cm mass in a renal allograft
.
Am J Transplant
.
2011 Oct
;
11
(
10
):
2242
6
.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.