Objective: Maximum urethral closure pressure (MUCP) and Valsalva leak point pressure (VLPP) have been considered objective parameters for studying the urethral integrity and predicting outcome after surgery for stress urinary incontinence (SUI). We test the hypothesis that preoperative MUCP and/or VLPP may predict long-term outcome after out-in transobturator tape (TOT) surgery for female SUI. Methods: 65 patients affected by stress or mixed urinary incontinence were enrolled in a prospective observational descriptive study conducted from May 2002 to November 2005 at a single tertiary urban teaching university urogynecological department. Preoperative MUCP and VLPP, stratified as ≤ or >40 cm H2O and ≤ or >60 cm H2O, respectively, were separately or in combination correlated with primary (continence status: dry or wet) and secondary outcome variables (quality of life questionnaires) after surgery. Results: Out of 65 patients, 6 (9.2%) did not attend the follow-up. The median follow-up was 46 months (mean 52 ± 18; range 36–82). The overall objective cure rates (dry) were 74.4% for patients with VLPP >60 cm H2O and 65% for VLPP ≤60 cm H2O (p < 0.654). The overall objective cure rates (dry) were 75% for patients with MUCP >40 cm H2O and 68.6% for MUCP ≤40 cm H2O (p < 0.808). The overall objective cure rates (dry) were 82.4% for patients with MUCP >40 cm H2O and VLPP >60 cm H2O and 69.2% for MUCP ≤40 cm H2O and VLPP ≤60 cm H2O (p < 0.956). Conclusions: These data seem to cast doubts on the predictive value of MUCP and VLPP in patients who underwent TOT.

Keywords:
Maximum urethral closure pressure, Valsalva leak point pressure, Stress urinary incontinence, Transobturator tape, outcome
This content is only available via PDF.
© 2009 S. Karger AG, Basel
2009
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.