After a complete obstruction of the ureter, renal function recovers more completely after diversion of the urine by splints than by ureterocystoneostomy. After a longer period of obstruction and successive restoration of urinary diversion by ureterocystoneostomy a relative increase in pressure of the ureter continues. This is the result of a functional obstruction, caused by disintegration of the muscle cells by connective tissue. The proliferation of connective tissue is probably induced and maintained by extravasation of urine into the layers of the ureter and that after abolition of the special function of the tunica mucosa. The defects of the mucosa are probably caused by metabolic disturbance after a pressure-induced decrease of blood supply.

Keywords:
Obstruction of the ureter, Ureterocystoneostomy, Renal function
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© 1980 S. Karger AG, Basel
1980
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